ANOVA PANCAN result package

Francesco Iorio, EMBL - European Bioinformatics Institute
result parsing started on 2016-03-31 19:02:12 iorio@ebi.ac.uk

Drug Domain: GDSC1000_paper_set, Analysis Domain: panCancer


Individual Feature analysis: loss_cnaPANCAN251, loss_cnaPANCAN252


Feature details and cell panel numbers

Binary feature equal to 1 for samples having the genomic region(s) cnaPANCAN251, loss_cnaPANCAN252 deleted (see genomic region decoding file for further infos on this region)

Number of cell lines positive for this feature: 80


Statistically significant associations identified = 2

association id	FEATURE	Drug id	Propr	Public	Drug Name	Drug Target	N FEATURE pos	N FEATURE neg	log max Conc tested	FEATURE neg logIC50 MEAN	FEATURE pos logIC50 MEAN	FEATURE deltaMEAN IC50	FEATURE IC50 effectSize	FEATURE neg Glass delta	FEATURE pos Glass delta	ANOVA FEATURE pval	Tissue ANOVA pval	MSI ANOVA pval	ANOVA FEATURE FDR %
a272	loss_cnaPANCAN251, loss_cnaPANCAN252	1170	1	1	CCT018159	HSP90	69	825	2.3	3.04	3.61	0.568	0.53 .	0.53 .	0.53 .	1.85e-04	2e-17	1.43e-03	11
a404	loss_cnaPANCAN251, loss_cnaPANCAN252	1026	1	1	17-AAG	HSP90	65	782	0	-0.597	0.0855	0.683	0.38	0.38	0.37	4.78e-04	2.73e-39	4.15e-01	20

All-tests volcano plot